The APC tumor suppressor is required for epithelial cell ...

由 J Yang 著作 · 2006 · 被引用 255 次 — APC is an important tumor suppressor for colorectal cancer. APC mutations are responsible for familial adenomatous polyposis and up to 85% of sporadic ...

2007年10月1日 — The adenomatous polyposis coli (APC) gene is a key tumor suppressor gene. Mutations in the gene have been found not only in most colon ...

2013年3月1日 — The APC protein acts as a tumor suppressor, which means that it ... Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional ...

由 Y Li 著作 · 2022 · 被引用 2 次 — We pinpointed the APC gene, which was mutated in 18 (18%) of 99 tumour samples, as a new potential biomarker for immunotherapy. Further analysis showed that ...

由 G Traverso 著作 · 2002 · 被引用 485 次 — The mutations in the adenomatous polyposis coli (APC) gene that initiate colorectal tumors theoretically provide an optimal marker for detecting colorectal ...

由 W Hankey 著作 · 2018 · 被引用 165 次 — It has recently emerged that APC mutational status has value as a predictive marker of poor prognosis in Stage III colorectal cancers [17], raising the ...

由 WB Du 著作 · 2019 · 被引用 13 次 — The upregulated expression of miR-451 in papillary thyroid carcinoma with lymph node metastasis is a unique marker for prognosis and progression ...

由 AC Lesko 著作 · 2015 · 被引用 38 次 — The Adenomatous Polyposis Coli (APC) tumor suppressor has been previously implicated in the control of apical–basal polarity; yet, the consequence of APC loss- ...